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Acetazolamide may produce an increased level of crystals in the urine. The reality is that Diamox is not a wonder drug. Delaney Below Deck. Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect. Popular Videos This Week. Acetazolamide acts as a noncompetitive inhibitor of carbonic anhydrase, of which there are several subtypes in humans. DIAMOX SEQUELS are extended-release capsules, for oral administration, each containing 500 mg of acetazolamide and the following inactive ingredients: Microcrystalline. It. 8-30 mg/kg/day orally once daily or divided every 12 hours. Dosage. Acetazolamide is also used to reduce the severity and duration of symptoms (upset stomach, headache, shortness of breath, dizziness, drowsiness, and fatigue) of altitude (mountain) sickness. Voksne. This medicine is available only with a doctor ¶s prescription. 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